Licorice Root Vs Dgl — Key Differences Explained
Licorice root has been used for centuries in traditional medicine, particularly for digestive support and respiratory health. Yet when browsing supplements today, you'll often encounter two distinct options: whole licorice root and DGL (deglycyrrhizinated licorice). Understanding the difference between these forms is essential for making an informed choice about which may better suit your wellness goals.
The primary distinction lies in a compound called glycyrrhizin. Whole licorice root contains this naturally occurring substance, which gives licorice its characteristic sweet taste but can also affect blood pressure and potassium levels when consumed regularly in significant amounts. DGL, by contrast, has had most of the glycyrrhizin removed through processing, creating a form that research suggests may support digestive comfort without the same cardiovascular considerations.
The Science Behind Licorice Root and DGL
Glycyrrhizin, the active compound in whole licorice root, has been studied for its anti-inflammatory and antimicrobial properties. It works by inhibiting certain enzymes in the body, which may explain why traditional practitioners have long valued licorice for respiratory and digestive applications. However, this same mechanism can lead to increased cortisol activity, potentially raising blood pressure and causing potassium depletion when used long-term or in high doses. The European Medicines Agency recommends limiting whole licorice root use to no more than four to six weeks without professional guidance.
DGL undergoes a specific extraction process that removes approximately 97% of the glycyrrhizin whilst preserving other beneficial plant compounds, including flavonoids and chalcones. Clinical research suggests that DGL may support the mucosal lining of the stomach and oesophagus, making it a popular choice for those seeking digestive comfort. A systematic review published in the Journal of Alternative and Complementary Medicine noted that DGL demonstrated promise in supporting gastric health without the blood pressure concerns associated with whole licorice root. Because the potentially problematic compound has been largely removed, DGL is generally considered suitable for longer-term use, though individual needs vary.
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Frequently Asked Questions
What does the evidence actually say about licorice root?
Clinical evidence suggests that licorice root may support digestive and respiratory health, primarily due to its anti-inflammatory and antimicrobial properties. However, long-term use of whole licorice root (containing glycyrrhizin) has been associated with elevated blood pressure and reduced potassium levels in some individuals. DGL, with glycyrrhizin removed, appears to retain digestive benefits whilst minimising cardiovascular concerns. Most clinical guidance recommends limiting whole licorice root to short-term use unless under professional supervision, whilst DGL may be more suitable for extended periods.
Can I take DGL and whole licorice root together?
Combining DGL with whole licorice root isn't typically recommended, as it would reintroduce the glycyrrhizin you're presumably trying to avoid by choosing DGL. If you're considering licorice supplementation for specific health concerns, it's best to select one form based on your individual needs and health status. Those with cardiovascular concerns, hypertension, or potassium imbalances generally fare better with DGL, whilst short-term use of whole licorice root may be appropriate for certain respiratory applications under professional guidance.
How quickly do licorice root and DGL work?
The timeframe varies depending on the intended use and individual physiology. For acute digestive discomfort, some people report noticing effects from DGL within a few days to two weeks of consistent use. Whole licorice root used for respiratory support may show effects within a similar window. However, supporting the underlying health of digestive tissues typically requires several weeks of regular use. As with any botanical supplement, consistency matters more than isolated doses, and individual responses can differ significantly based on overall health, diet, and the specific concern being addressed.
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